At least 13 people have been killed after a car bomb exploded near a police station in the Syrian capital of Damascus.
A state official speaking from the scene said an explosives-rigged taxi blew up 50 metres from the Bab Touma neighbourhood's main police station.
The mainly Christian neighbourhood is a popular attraction for shoppers and inhabited mostly by the Christian minority.
Pro-government television said seven people had been killed and 15 wounded.
Mr Assad has met with UN peace envoy Lakhdar Brahimi The Britain-based Syrian Observatory for Human Rights reported 10 had died and dozens were wounded, adding that it was unclear if the victims and the wounded were civilians or policemen.
A reporter at the scene said he saw blood stains in the street and on the pavements. He said glass windows of several shops in the area were shattered and at least four cars were completely burnt.
The blast came as President Bashar al Assad opened talks with visiting UN peace envoy Lakhdar Brahimi, who is trying to broker a truce to start during a Muslim holiday this week.
Mr Brahimi told reporters following a closed-door meeting that he had earlier met with unidentified Syrian opposition groups inside and outside the country to consult on his truce plan.
He said he received "promises" but not a "commitment" from them to honour the cease-fire.
"There is a promise to stop fighting," he said, referring to the opposition.
He noted that he "found an overwhelming response" from Mr Assad's opponents to his cease-fire plan and that "all of them have said that it's a good idea which they support."
State news agency Sana said the president supported "any sincere effort to find a political solution to the crisis, based on respect for Syrian sovereignty and rejecting foreign intervention".
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